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IMMU-40. SINGLE-CELL LEVEL COMPARISON OF HISTOPATHOLOGY AND SINGLE-CELL RNA-SEQ DATABASES BETWEEN IDH-MUT AND –WT GLIOBLASTOMAS REVEALS DISTINCT INNATE IMMUNE MICROENVIRONMENTS THAT CAN BE EXPLOITED FOR THERAPEUTIC GAIN
BACKGROUND: Most immune cells in the glioblastoma (GBM) microenvironment are microglia and macrophages (MMs), but they are poorly understood. We sought to characterize these innate immune cells in human untreated IDH-WT and rare IDH-MUT GBM tissue to elucidate differences underlying their disparate...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216379/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.543 |
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