TMIC-08. CHD7 IS SUPPRESSED IN THE PERINECROTIC/ISCHEMIC MICROENVIRONMENT AND IS A NOVEL REGULATOR OF ANGIOGENESIS

A pathologic hallmark of glioblastoma (GBM), the most common and deadly primary brain tumor in adults, is pseudopalisading necrotic regions in which ischemic conditions are found. Ischemic microenvironments characterized by low oxygen, restricted glucose, and acidic pH due to poor blood supply occur...

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Publicado en:Neuro Oncol
Autores principales: Boyd, Nathaniel, Ayokanmbi, Adetokunbo, Walker, Kiera, Whetsel, Julia, Gordillo, Juan, Smith, Cynthia, Gordon, Emily, Herting, Cameron, Hambardzumyan, Dolores, Gillespie, Yancey, Hackney, James, Cooper, Sara, Jiao, Kai, Hjelmeland, Anita
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216337/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1068
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