DDIS-25. TARGETING GLIOBLASTOMA HETEROGENEITY WITH miR-34a

microRNA-34a could serve as a novel therapeutic agent as it is under-expressed in Glioblastoma and modulates the expression of multiple genes in the deregulated p53, Rb and receptor tyrosine kinase networks which confer selective growth advantage and represent significant intra-tumoral heterogeneity...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Khan, Muhammad, Ruggieri, Rosamaria, Tran, Nhan, Sarkaria, Jann, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Boockvar, John, Symons, Marc
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216330/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.304
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