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EXTH-05. miR-34a INHIBITS GLIOBLASTOMA CELL PROLIFERATION AND SENSITIZES TO TEMOZOLOMIDE

Glioblastoma (GBM) is the most common primary brain tumor with a median survival of 14.5 months, despite maximal therapy consisting of surgical resection, radiation and temozolomide (TMZ). Genetic profiling has shown an average of three driver mutations localized to the p53, Rb and receptor tyrosine...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Khan, Muhammad Babar, Ruggieri, Rosamaria, Tran, Nhan, Sarkaria, Jann, Symons, Marc
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691989/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.301
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