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STEM-23. miR-486-5p REGULATES TUMOR SUPPRESSOR NETWORKS AND ITS INHIBITION REDUCES TUMOR VOLUME AND SENSITIZES TO RADIATION TREATMENT IN A PDX MOUSE MODEL OF GBM
Glioblastoma multiforme (GBM) is a heterogeneous malignancy that contains a subpopulation of tumor cells with stem-like features. These GBM stem cells (GSCs) have the ability to self-renew and establish tumors. As such, they are thought to disproportionately contribute to re-growth and resistance to...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216229/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1030 |
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