In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by dopaminergic neuron loss. At present, there are no drugs that stop the progression of PD. As with other multifactorial genetic disorders, genome-wide association studies (GWASs) found multiple risk loci for PD, although their...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Uenaka, Takeshi, Satake, Wataru, Cha, Pei-Chieng, Hayakawa, Hideki, Baba, Kousuke, Jiang, Shiying, Kobayashi, Kazuhiro, Kanagawa, Motoi, Okada, Yukinori, Mochizuki, Hideki, Toda, Tatsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Association Studies Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216208/
https://ncbi.nlm.nih.gov/pubmed/30137437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy279
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge