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ATIM-19. RESULTS OF THE GLOBE STUDY: A PHASE 3, RANDOMIZED, CONTROLLED, DOUBLE-ARM, OPEN-LABEL, MULTI-CENTER STUDY OF VB-111 COMBINED WITH BEVACIZUMAB VS. BEVACIZUMAB MONOTHERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA

BACKGROUND: Ofranergene obadenovec (VB-111) is a viral cancer-therapy with a dual mechanism: vascular disruption and induction of a tumor directed immune response. In a phase 2 trial, recurrent GBM (rGBM) patients treated with VB-111, followed at progression with VB-111 in combination with bevacizum...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Cloughesy, Timothy, Brenner, Andrew J, Butowski, Nicholas, Cohen, Yael C, Lowenton-Spier, Noa, Wen, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216132/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.014
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