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NIMG-47. VOLUMETRIC ANALYSIS OF PHASE 2 AND 3 TRIALS IN RECURRENT GLIOBLASTOMA TREATED WITH VB-111 WITH OR WITHOUT BEVACIZUMAB OR BEVACIZUMAB MONOTHERAPY

VB-111 is a non-replicating adenovirus carrying a pro-apoptotic transgene for TNFR1/Fas under the control of a modified murine promoter to pre-proendothelin 1. The transgene is expressed only in angiogenic endothelial cells, and therefore VB-111 results in targeted apoptosis of neovascular vessels....

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ellingson, Benjamin, Raymond, Catalina, Yao, Jingwen, Goldman, Jodi, Schlossman, Jacob, Tran, Caleb, Brenner, Andrew, Butowski, Nicholas, Wen, Patrick, Rachmilewitz Minei, Tamar, Cohen, Yael, Harats, Dror, Cloughesy, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847735/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.717
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