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ATIM-10. A PHASE I/II CLINICAL TRIAL OF AUTOLOGOUS CMV-SPECIFIC CYTOTOXIC T CELLS (CMV-TC) FOR GLIOBLASTOMA: DOSE ESCALATION AND CORRELATIVE RESULTS
BACKGROUND: Cytomegalovirus (CMV) antigens are present in > 90% of GBMs but not in normal brain. CMV-TC in GBM tumor tissue have their effector function suppressed. Highly functional CMV pp65 specific T cells can be expanded in vitro from peripheral blood (PB) of GBM patients. METHODS: Autologous...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216121/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.006 |
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