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Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis

The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the lethal disease alveolar echinococcosis. Current chemotherapeutic treatment options are based on benzimidazoles (albendazole and mebendazole), which are insufficient and hence alternative drugs are needed. In this study,...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Rufener, Reto, Dick, Luca, D'Ascoli, Laura, Ritler, Dominic, Hizem, Amani, Wells, Timothy N.C., Hemphill, Andrew, Lundström-Stadelmann, Britta
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216040/
https://ncbi.nlm.nih.gov/pubmed/30396011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.10.011
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