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Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis

The current chemotherapeutical treatment against alveolar echinococcosis relies exclusively on benzimidazoles, which are not parasiticidal and can induce severe toxicity. There are no alternative treatment options. To identify novel drugs with activity against Echinococcus multilocularis metacestode...

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Bibliografiske detaljer
Udgivet i:Int J Parasitol Drugs Drug Resist
Main Authors: Lundström-Stadelmann, Britta, Rufener, Reto, Hemphill, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7389337/
https://ncbi.nlm.nih.gov/pubmed/32636148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2020.06.002
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