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Enhancement of precursor amino acid supplies for improving bacitracin production by activation of branched chain amino acid transporter BrnQ and deletion of its regulator gene lrp in Bacillus licheniformis

Bacitracin, a new type of cyclic peptide antibiotic, is widely used as the feed additive in feed industry. Branched chain amino acids (BCAAs) are the key precursors for bacitracin synthesis. In this research, soybean meal was served as the raw material to supply precursor amino acids for bacitracin...

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Bibliografiske detaljer
Udgivet i:Synth Syst Biotechnol
Main Authors: Zhu, Jiang, Cai, Dongbo, Xu, Haixia, Liu, Ziwei, Zhang, Bowen, Wu, Fei, Li, Junhui, Chen, Shouwen
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Publishing 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215969/
https://ncbi.nlm.nih.gov/pubmed/30417137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2018.10.009
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