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Enhancement of precursor amino acid supplies for improving bacitracin production by activation of branched chain amino acid transporter BrnQ and deletion of its regulator gene lrp in Bacillus licheniformis

Bacitracin, a new type of cyclic peptide antibiotic, is widely used as the feed additive in feed industry. Branched chain amino acids (BCAAs) are the key precursors for bacitracin synthesis. In this research, soybean meal was served as the raw material to supply precursor amino acids for bacitracin...

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Detalhes bibliográficos
Publicado no:Synth Syst Biotechnol
Main Authors: Zhu, Jiang, Cai, Dongbo, Xu, Haixia, Liu, Ziwei, Zhang, Bowen, Wu, Fei, Li, Junhui, Chen, Shouwen
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215969/
https://ncbi.nlm.nih.gov/pubmed/30417137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2018.10.009
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