Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1

Cholangiocarcinoma is a life‐threatening disease with a poor prognosis. Although genome analysis unraveled some genetic mutation profiles in cholangiocarcinoma, it remains unknown whether such genetic abnormalities relate to the effects of anticancer drugs. Mutations in isocitrate dehydrogenase 1 an...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Fujiwara, Hiroaki, Tateishi, Keisuke, Kato, Hiroyuki, Nakatsuka, Takuma, Yamamoto, Keisuke, Tanaka, Yasuo, Ijichi, Hideaki, Takahara, Naminatsu, Mizuno, Suguru, Kogure, Hirofumi, Matsubara, Saburo, Nakai, Yousuke, Koike, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215870/
https://ncbi.nlm.nih.gov/pubmed/30156013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13784
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