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CD8(+) T-cell density imaging with (64)Cu-labeled cys-diabody informs immunotherapy protocols

PURPOSE: Noninvasive and quantitative tracking of CD8(+) T-cells by positron emission tomography (PET) has emerged as a potential technique to gauge response to immunotherapy. We apply an anti-CD8 cys-diabody, labeled with (64)Cu, to assess the sensitivity of PET imaging of normal and diseased tissu...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Seo, Jai Woong, Tavaré, Richard, Mahakian, Lisa M., Silvestrini, Matthew T., Tam, Sarah, Ingham, Elizabeth S., Salazar, Felix B., Borowsky, Alexander D., Wu, Anna M., Ferrara, Katherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215696/
https://ncbi.nlm.nih.gov/pubmed/29967252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0261
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