Transition-transversion encoding and genetic relationship metric in ReliefF feature selection improves pathway enrichment in GWAS

BACKGROUND: ReliefF is a nearest-neighbor based feature selection algorithm that efficiently detects variants that are important due to statistical interactions or epistasis. For categorical predictors, like genotypes, the standard metric used in ReliefF has been a simple (binary) mismatch differenc...

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Dades bibliogràfiques
Publicat a:BioData Min
Autors principals: Arabnejad, M., Dawkins, B. A., Bush, W. S., White, B. C., Harkness, A. R., McKinney, B. A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Methodology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215626/
https://ncbi.nlm.nih.gov/pubmed/30410580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-018-0186-4
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