Transition-transversion encoding and genetic relationship metric in ReliefF feature selection improves pathway enrichment in GWAS

BACKGROUND: ReliefF is a nearest-neighbor based feature selection algorithm that efficiently detects variants that are important due to statistical interactions or epistasis. For categorical predictors, like genotypes, the standard metric used in ReliefF has been a simple (binary) mismatch differenc...

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Bibliografiske detaljer
Udgivet i:BioData Min
Main Authors: Arabnejad, M., Dawkins, B. A., Bush, W. S., White, B. C., Harkness, A. R., McKinney, B. A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215626/
https://ncbi.nlm.nih.gov/pubmed/30410580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-018-0186-4
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