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Kindlin-2 interacts with a highly conserved surface of ILK to regulate focal adhesion localization and cell spreading

The integrin-associated adaptor proteins integrin-linked kinase (ILK) and kindlin-2 play central roles in integrin signaling and control of cell morphology. A direct ILK–kindlin-2 interaction is conserved across species and involves the F2PH subdomain of kindlin-2 and the pseudokinase domain (pKD) o...

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Publicat a:J Cell Sci
Autors principals: Kadry, Yasmin A., Huet-Calderwood, Clotilde, Simon, Bertrand, Calderwood, David A.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215391/
https://ncbi.nlm.nih.gov/pubmed/30254023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.221184
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