Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s disease

BACKGROUND: Biomarkers that can track disease onset and progression in autosomal dominant Alzheimer’s disease (ADAD) are needed. We investigate whether serum neurofilament light (NfL) concentration is associated with clinical and cerebrospinal fluid (CSF) markers in ADAD. We also evaluate serum NfL...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Sánchez-Valle, Raquel, Heslegrave, Amanda, Foiani, Martha S., Bosch, Beatriz, Antonell, Anna, Balasa, Mircea, Lladó, Albert, Zetterberg, Henrik, Fox, Nick C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215337/
https://ncbi.nlm.nih.gov/pubmed/30390718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0439-y
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