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Suppressive effect of syndecan ectodomains and N-desulfated heparins on osteoclastogenesis via direct binding to macrophage-colony stimulating factor

Syndecans, a family of cell surface heparan sulfate proteoglycans, regulate cell differentiation via binding of their heparan sulfate chains to growth factors and cytokines and play a role in tumor growth and progression, wound repair, and intestinal mucosal damage. However, the functional and mecha...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Kim, Jin-Man, Lee, Kyunghee, Kim, Mi Yeong, Shin, Hong-In, Jeong, Daewon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215006/
https://ncbi.nlm.nih.gov/pubmed/30389911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1167-8
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