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An information-theoretic framework for deciphering pleiotropic and noisy biochemical signaling
Many components of signaling pathways are functionally pleiotropic, and signaling responses are marked with substantial cell-to-cell heterogeneity. Therefore, biochemical descriptions of signaling require quantitative support to explain how complex stimuli (inputs) are encoded in distinct activities...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6214929/ https://ncbi.nlm.nih.gov/pubmed/30389942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07085-1 |
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