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Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamics

BACKGROUND: Compared to engineering or physics problems, dynamical models in quantitative biology typically depend on a relatively large number of parameters. Progress in developing mathematics to manipulate such multi-parameter models and so enable their efficient interplay with experiments has bee...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Nienałtowski, Karol, Włodarczyk, Michał, Lipniacki, Tomasz, Komorowski, Michał
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587803/
https://ncbi.nlm.nih.gov/pubmed/26415494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0205-8
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