Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity

High-grade gliomas (HGGs) are the most aggressive and invasive primary brain tumors. The platelet-derived growth factor (PDGF) signaling pathway drives HGG progression, and enhanced expression of PDGF receptors (PDGFRs) is a well-established aberration in a subset of glioblastomas (GBMs). PDGFRA is...

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Veröffentlicht in:iScience
Hauptverfasser: Wallmann, Tatjana, Zhang, Xing-Mei, Wallerius, Majken, Bolin, Sara, Joly, Anne-Laure, Sobocki, Caroline, Leiss, Lina, Jiang, Yiwen, Bergh, Jonas, Holland, Eric C., Enger, Per Ø., Andersson, John, Swartling, Fredrik J., Miletic, Hrvoje, Uhrbom, Lene, Harris, Robert A., Rolny, Charlotte
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214839/
https://ncbi.nlm.nih.gov/pubmed/30384135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.10.011
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