Taxol Induces Brk-dependent Pro-survival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis

The metastatic cascade is a complex process that requires cancer cells to survive despite conditions of high physiologic stress. Previously a cooperation between the glucocorticoid receptor (GR) and hypoxia inducible factors (HIFs) was reported as a point of convergence for host and cellular stress...

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Gepubliceerd in:Mol Cancer Res
Hoofdauteurs: Anderson, Tarah M Regan, Ma, Shihong, Kerkvliet, Carlos Perez, Peng, Yan, Helle, Taylor M, Krutilina, Raisa I, Raj, Ganesh V, Cidlowski, John A, Ostrander, Julie H, Schwertfeger, Kathryn L, Seagroves, Tiffany N, Lange, Carol A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214723/
https://ncbi.nlm.nih.gov/pubmed/29991529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0410
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