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HIGHLY STEREOSELECTIVE REDUCTION OF α-KETO ESTERS: UTILITY OF CIS-1-ARYLSULFONAMIDO-2-INDANOLS AS CHIRAL AUXILIARIES

The reduction of α-keto esters bearing cis-1-arylsulfonamido-2-indanol derivatives proceeded with high diastereoselectivities providing the corresponding α-hydroxy esters in excellent yields. The chiral auxiliary group is removed under mild basic conditions and recovered.

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Dades bibliogràfiques
Publicat a:Tetrahedron Lett
Autors principals: Ghosh, Arun K., Chen, Yan
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214205/
https://ncbi.nlm.nih.gov/pubmed/30393406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0040-4039(95)01385-U
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