The Emerging Role of Cyclin-Dependent Kinases (CDKs) in Pancreatic Ductal Adenocarcinoma

The family of cyclin-dependent kinases (CDKs) has critical functions in cell cycle regulation and controlling of transcriptional elongation. Moreover, dysregulated CDKs have been linked to cancer initiation and progression. Pharmacological CDK inhibition has recently emerged as a novel and promising...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: García-Reyes, Balbina, Kretz, Anna-Laura, Ruff, Jan-Philipp, von Karstedt, Silvia, Hillenbrand, Andreas, Knippschild, Uwe, Henne-Bruns, Doris, Lemke, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214075/
https://ncbi.nlm.nih.gov/pubmed/30340359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103219
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