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The Emerging Role of Cyclin-Dependent Kinases (CDKs) in Pancreatic Ductal Adenocarcinoma

The family of cyclin-dependent kinases (CDKs) has critical functions in cell cycle regulation and controlling of transcriptional elongation. Moreover, dysregulated CDKs have been linked to cancer initiation and progression. Pharmacological CDK inhibition has recently emerged as a novel and promising...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: García-Reyes, Balbina, Kretz, Anna-Laura, Ruff, Jan-Philipp, von Karstedt, Silvia, Hillenbrand, Andreas, Knippschild, Uwe, Henne-Bruns, Doris, Lemke, Johannes
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214075/
https://ncbi.nlm.nih.gov/pubmed/30340359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103219
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