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Thrombospondin-1 Is Necessary for the Development and Repair of Corneal Nerves

Thrombospondin-1-deficient (TSP-1(−/−)) mice are used as an animal model of Sjögren’s Syndrome because they exhibit many of the symptoms associated with the autoimmune type of dry eye found in primary Sjögren’s Syndrome. This type of dry eye is linked to the inflammation of the lacrimal gland, conju...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Tatematsu, Yukako, Khan, Qalbi, Blanco, Tomas, Bair, Jeffrey A., Hodges, Robin R., Masli, Sharmila, Dartt, Darlene A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214039/
https://ncbi.nlm.nih.gov/pubmed/30332778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103191
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