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Alteration in Nerves and Neurotransmitter Stimulation of Lacrimal Gland Secretion in the TSP-1(−/−) Mouse Model of Aqueous Deficiency Dry Eye

The purpose of this study is to determine neural, vascular, protein secretion, and cellular signaling changes with disease progression in lacrimal glands of the thrombospondin-1(−/−) (TSP-1(−/−)) mouse model of dry eye compared to C57BL/6 wild type (WT) mice. Neural innervation was reduced in TSP-1(...

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Dades bibliogràfiques
Publicat a:Mucosal Immunol
Autors principals: Bhattacharya, Sumit, Garcia-Posadas, Laura, Hodges, Robin R., Makarenkova, Helen P., Masli, Sharmila, Dartt, Darlene A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030454/
https://ncbi.nlm.nih.gov/pubmed/29445135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0002-y
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