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Exploring Configuration Space and Path Space of Biomolecules Using Enhanced Sampling Techniques—Searching for Mechanism and Kinetics of Biomolecular Functions

To understand functions of biomolecules such as proteins, not only structures but their conformational change and kinetics need to be characterized, but its atomistic details are hard to obtain both experimentally and computationally. Here, we review our recent computational studies using novel enha...

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Pubblicato in:Int J Mol Sci
Autori principali: Fujisaki, Hiroshi, Moritsugu, Kei, Matsunaga, Yasuhiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213965/
https://ncbi.nlm.nih.gov/pubmed/30326661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103177
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