Systemic Administration and Targeted Delivery of Immunogenic Oncolytic Adenovirus Encapsulated in Extracellular Vesicles for Cancer Therapies

Oncolytic viruses (OV) are engineered to infect, replicate in and kill cancer cells. Currently, the OV therapeutic approach is mainly restricted to neoplasia amenable to direct local administration of viral particles, while the possibility of a systemic delivery of cancer-tropic viruses would extend...

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Bibliographic Details
Published in:Viruses
Main Authors: Garofalo, Mariangela, Villa, Alessandro, Rizzi, Nicoletta, Kuryk, Lukasz, Mazzaferro, Vincenzo, Ciana, Paolo
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213631/
https://ncbi.nlm.nih.gov/pubmed/30322158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10100558
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