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Nonsense‐mediated mRNA decay involves two distinct Upf1‐bound complexes
Nonsense‐mediated mRNA decay (NMD) is a translation‐dependent RNA degradation pathway involved in many cellular pathways and crucial for telomere maintenance and embryo development. Core NMD factors Upf1, Upf2 and Upf3 are conserved from yeast to mammals, but a universal NMD model is lacking. We use...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6213285/ https://ncbi.nlm.nih.gov/pubmed/30275269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899278 |
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