Nonsense‐mediated mRNA decay involves two distinct Upf1‐bound complexes

Nonsense‐mediated mRNA decay (NMD) is a translation‐dependent RNA degradation pathway involved in many cellular pathways and crucial for telomere maintenance and embryo development. Core NMD factors Upf1, Upf2 and Upf3 are conserved from yeast to mammals, but a universal NMD model is lacking. We use...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Dehecq, Marine, Decourty, Laurence, Namane, Abdelkader, Proux, Caroline, Kanaan, Joanne, Le Hir, Hervé, Jacquier, Alain, Saveanu, Cosmin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213285/
https://ncbi.nlm.nih.gov/pubmed/30275269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899278
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