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Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation
Self‐renewal of embryonic stem cells (ESCs) cultured in LIF/fetal calf serum (FCS) is incomplete with some cells initiating differentiation. While this is reflected in heterogeneous expression of naive pluripotency transcription factors (TFs), the link between TF heterogeneity and differentiation is...
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| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6213284/ https://ncbi.nlm.nih.gov/pubmed/30275266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695476 |
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