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More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand
Guanine-rich nucleic acid sequences can fold into four-stranded G-quadruplex (G4) structures. Despite growing evidence for their biological significance, considerable work still needs to be done to detail their cellular occurrence and functions. Herein, we describe an optimized core-extended naphtha...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6212845/ https://ncbi.nlm.nih.gov/pubmed/29986058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky607 |
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