Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography

A focused library of newly designed monomeric and dimeric naphthalene diimides (NDIs) was analyzed in its ability to recognize specific G-quadruplex (G4) structures discriminating duplex DNA. The best G4 ligands—according to an affinity chromatography-based screening method named G4-CPG—were tested...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Platella, Chiara, Pirota, Valentina, Musumeci, Domenica, Rizzi, Federica, Iachettini, Sara, Zizza, Pasquale, Biroccio, Annamaria, Freccero, Mauro, Montesarchio, Daniela, Doria, Filippo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139804/
https://ncbi.nlm.nih.gov/pubmed/32183038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21061964
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki