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Misfolding of a DNAzyme for ultrahigh sodium selectivity over potassium
Herein, the excellent Na(+) selectivity of a few RNA-cleaving DNAzymes was exploited, where Na(+) can be around 3000-fold more effective than K(+) for promoting catalysis. By using a double mutant based on the Ce13d DNAzyme, and by lowering the temperature, increased 2-aminopurine (2AP) fluorescence...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6212836/ https://ncbi.nlm.nih.gov/pubmed/30215808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky807 |
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