A Secreted Bacterial Peptidylarginine Deiminase Can Neutralize Human Innate Immune Defenses

The keystone oral pathogen Porphyromonas gingivalis is associated with severe periodontitis. Intriguingly, this bacterium is known to secrete large amounts of an enzyme that converts peptidylarginine into citrulline residues. The present study was aimed at identifying possible functions of this citr...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Stobernack, Tim, du Teil Espina, Marines, Mulder, Lianne M., Palma Medina, Laura M., Piebenga, Dillon R., Gabarrini, Giorgio, Zhao, Xin, Janssen, Koen M. J., Hulzebos, Jarnick, Brouwer, Elisabeth, Sura, Thomas, Becher, Dörte, van Winkelhoff, Arie Jan, Götz, Friedrich, Otto, Andreas, Westra, Johanna, van Dijl, Jan Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212822/
https://ncbi.nlm.nih.gov/pubmed/30377277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01704-18
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