A Secreted Bacterial Peptidylarginine Deiminase Can Neutralize Human Innate Immune Defenses

The keystone oral pathogen Porphyromonas gingivalis is associated with severe periodontitis. Intriguingly, this bacterium is known to secrete large amounts of an enzyme that converts peptidylarginine into citrulline residues. The present study was aimed at identifying possible functions of this citr...

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Библиографические подробности
Опубликовано в: :mBio
Главные авторы: Stobernack, Tim, du Teil Espina, Marines, Mulder, Lianne M., Palma Medina, Laura M., Piebenga, Dillon R., Gabarrini, Giorgio, Zhao, Xin, Janssen, Koen M. J., Hulzebos, Jarnick, Brouwer, Elisabeth, Sura, Thomas, Becher, Dörte, van Winkelhoff, Arie Jan, Götz, Friedrich, Otto, Andreas, Westra, Johanna, van Dijl, Jan Maarten
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212822/
https://ncbi.nlm.nih.gov/pubmed/30377277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01704-18
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