A Secreted Bacterial Peptidylarginine Deiminase Can Neutralize Human Innate Immune Defenses

The keystone oral pathogen Porphyromonas gingivalis is associated with severe periodontitis. Intriguingly, this bacterium is known to secrete large amounts of an enzyme that converts peptidylarginine into citrulline residues. The present study was aimed at identifying possible functions of this citr...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Stobernack, Tim, du Teil Espina, Marines, Mulder, Lianne M., Palma Medina, Laura M., Piebenga, Dillon R., Gabarrini, Giorgio, Zhao, Xin, Janssen, Koen M. J., Hulzebos, Jarnick, Brouwer, Elisabeth, Sura, Thomas, Becher, Dörte, van Winkelhoff, Arie Jan, Götz, Friedrich, Otto, Andreas, Westra, Johanna, van Dijl, Jan Maarten
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212822/
https://ncbi.nlm.nih.gov/pubmed/30377277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01704-18
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