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Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase

Some DNA transposons relocate from one genomic location to another using a mechanism that involves generating double-strand breaks at their transposon ends by forming hairpins on flanking DNA. The same double-strand break mode is employed by the V(D)J recombinase at signal-end/coding-end junctions d...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Hickman, Alison B, Voth, Andrea Regier, Ewis, Hosam, Li, Xianghong, Craig, Nancy L, Dyda, Fred
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212770/
https://ncbi.nlm.nih.gov/pubmed/30239795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky838
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