The Melanocortin MC5R as a New Target for Treatment of High Glucose-Induced Hypertrophy of the Cardiac H9c2 Cells

The study explored the anti-hypertrophic effect of the melanocortin MC5R stimulation in H9c2 cardiac myocytes exposed to high glucose. This has been done by using α-MSH and selective MC5R agonists and assessing the expression of GLUT4 and GLUT1 transporters, miR-133 and urotensin receptor levels as...

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Publicat a:Front Physiol
Autors principals: Trotta, Maria Consiglia, Maisto, Rosa, Alessio, Nicola, Hermenean, Anca, D’Amico, Michele, Di Filippo, Clara
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212602/
https://ncbi.nlm.nih.gov/pubmed/30416452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01475
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