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Design of metalloproteins and novel protein folds using variational autoencoders

The design of novel proteins has many applications but remains an attritional process with success in isolated cases. Meanwhile, deep learning technologies have exploded in popularity in recent years and are increasingly applicable to biology due to the rise in available data. We attempt to link pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Greener, Joe G., Moffat, Lewis, Jones, David T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212568/
https://ncbi.nlm.nih.gov/pubmed/30385875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34533-1
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