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Design of metalloproteins and novel protein folds using variational autoencoders

The design of novel proteins has many applications but remains an attritional process with success in isolated cases. Meanwhile, deep learning technologies have exploded in popularity in recent years and are increasingly applicable to biology due to the rise in available data. We attempt to link pro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Greener, Joe G., Moffat, Lewis, Jones, David T
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212568/
https://ncbi.nlm.nih.gov/pubmed/30385875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34533-1
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