Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

Most expression quantitative trait locus (eQTL) studies to date have been performed in heterogeneous tissues as opposed to specific cell types. To better understand the cell-type–specific regulatory landscape of human melanocytes, which give rise to melanoma but account for <5% of typical human s...

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Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Zhang, Tongwu, Choi, Jiyeon, Kovacs, Michael A., Shi, Jianxin, Xu, Mai, Goldstein, Alisa M., Trower, Adam J., Bishop, D. Timothy, Iles, Mark M., Duffy, David L., MacGregor, Stuart, Amundadottir, Laufey T., Law, Matthew H., Loftus, Stacie K., Pavan, William J., Brown, Kevin M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211648/
https://ncbi.nlm.nih.gov/pubmed/30333196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233304.117
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