From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

The paper focussed on a step-by-step structural modification of a cycloheptathiophene-3-carboxamide derivative recently identified by us as reverse transcriptase (RT)-associated ribonuclease H (RNase H) inhibitor. In particular, its conversion to a 2-aryl-cycloheptathienoozaxinone derivative and the...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Massari, Serena, Corona, Angela, Distinto, Simona, Desantis, Jenny, Caredda, Alessia, Sabatini, Stefano, Manfroni, Giuseppe, Felicetti, Tommaso, Cecchetti, Violetta, Pannecouque, Christophe, Maccioni, Elias, Tramontano, Enzo, Tabarrini, Oriana
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211256/
https://ncbi.nlm.nih.gov/pubmed/30362381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1523901
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky