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Real-Time Determination of the Cell-Cycle Position of Individual Cells within Live Tumors Using FUCCI Cell-Cycle Imaging

Most cytotoxic agents have limited efficacy for solid cancers. Cell-cycle phase analysis at the single-cell level in solid tumors has shown that the majority of cancer cells in tumors is not cycling and is therefore resistant to cytotoxic chemotherapy. Intravital cell-cycle imaging within tumors dem...

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Библиографические подробности
Опубликовано в: :Cells
Главные авторы: Yano, Shuya, Hoffman, Robert M.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210921/
https://ncbi.nlm.nih.gov/pubmed/30322204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7100168
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