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Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells

Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene (ESR1) regulation after hormonal stimulation, how it is regulated in hormone-free condition is not...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Verde, Gaetano, Llobet, Lara I. De, Wright, Roni H.G., Quilez, Javier, Peiró, Sandra, Dily, François Le, Beato, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210734/
https://ncbi.nlm.nih.gov/pubmed/30301163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10100371
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