Coordinated Biosynthesis of the Purine Nucleoside Antibiotics Aristeromycin and Coformycin in Actinomycetes

Purine nucleoside antibiotic pairs, concomitantly produced by a single strain, are an important group of microbial natural products. Here, we report a target-directed genome mining approach to elucidate the biosynthesis of the purine nucleoside antibiotic pair aristeromycin (ARM) and coformycin (COF...

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Detalles Bibliográficos
Publicado en:Appl Environ Microbiol
Main Authors: Xu, Gudan, Kong, Liyuan, Gong, Rong, Xu, Liudong, Gao, Yaojie, Jiang, Ming, Cai, You-Sheng, Hong, Kui, Hu, Youcai, Liu, Peng, Deng, Zixin, Price, Neil P. J., Chen, Wenqing
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
Assuntos:
Genetics and Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210108/
https://ncbi.nlm.nih.gov/pubmed/30217843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01860-18
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