Tumor–Stroma Cross-Talk in Human Pancreatic Ductal Adenocarcinoma: A Focus on the Effect of the Extracellular Matrix on Tumor Cell Phenotype and Invasive Potential

The extracellular matrix (ECM) in the tumor microenvironment modulates the cancer cell phenotype, especially in pancreatic ductal adenocarcinoma (PDAC), a tumor characterized by an intense desmoplastic reaction. Because the epithelial-to-mesenchymal transition (EMT), a process that provides cancer c...

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Опубликовано в: :Cells
Главные авторы: Procacci, Patrizia, Moscheni, Claudia, Sartori, Patrizia, Sommariva, Michele, Gagliano, Nicoletta
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209911/
https://ncbi.nlm.nih.gov/pubmed/30301152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7100158
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