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Tumor–Stroma Cross-Talk in Human Pancreatic Ductal Adenocarcinoma: A Focus on the Effect of the Extracellular Matrix on Tumor Cell Phenotype and Invasive Potential

The extracellular matrix (ECM) in the tumor microenvironment modulates the cancer cell phenotype, especially in pancreatic ductal adenocarcinoma (PDAC), a tumor characterized by an intense desmoplastic reaction. Because the epithelial-to-mesenchymal transition (EMT), a process that provides cancer c...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Procacci, Patrizia, Moscheni, Claudia, Sartori, Patrizia, Sommariva, Michele, Gagliano, Nicoletta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209911/
https://ncbi.nlm.nih.gov/pubmed/30301152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7100158
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