Combined Effect of Bortezomib and Menadione Sodium Bisulfite on Proteasomes of Tumor Cells: The Dramatic Decrease of Bortezomib Toxicity in a Preclinical Trial

Tumor growth is associated with elevated proteasome expression and activity. This makes proteasomes a promising target for antitumor drugs. Current antitumor drugs such as bortezomib that inhibit proteasome activity have significant side effects. The purpose of the present study was to develop effec...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Astakhova, Tatiana M., Morozov, Alexey V., Erokhov, Pavel A., Mikhailovskaya, Maria I., Akopov, Sergey B., Chupikova, Natalia I., Safarov, Ruslan R., Sharova, Natalia P.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209890/
https://ncbi.nlm.nih.gov/pubmed/30257462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10100351
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker